Guarana
Guarana (Paullinia cupana) is a climbing plant native to the Amazon basin, whose seeds are naturally rich in caffeine (guaranine), theobromine, and theophylline. In gummy manufacturing, it is used as a botanical source of sustained-release energy and mental alertness. As a botanical on the EFSA on-hold list, Guarana has no authorised health claims under EU Regulation 432/2012; claim coverage is achieved through co-formulated nutrients such as B-vitamins for energy-yielding metabolism.
- natural energy
- mental alertness
- sustained release
At a glance
- Definition
- Guarana (Paullinia cupana) is a climbing plant native to the Amazon basin, whose seeds are naturally rich in caffeine (guaranine), theobromine, and theophylline. In gummy manufacturing, it is used as a botanical source of sustained-release energy and mental alertness. As a botanical on the EFSA on-hold list, Guarana has no authorised health claims under EU Regulation 432/2012; claim coverage is achieved through co-formulated nutrients such as B-vitamins for energy-yielding metabolism.
- Common positionings
- natural energy
- mental focus
- sustained vitality
- pre-workout energy
- cognitive performance
- Format suitability
- Reviewed for gummies and sachets — confirmed per project.
Where this ingredient fits in the DAT Supply catalogue
Every format chip links through to its manufacturing hub and to the private-label catalogue for that format. The category chip routes to the matching vertical hub on the categories index.
- Botanicals & mushrooms
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What it is
Guarana is a botanical ingredient derived from the seeds of the Paullinia cupana plant, native to the Amazon rainforest. It is one of the most familiar and commercially understood natural energy ingredients across EU and US markets, valued for its sustained-release caffeine profile that provides alertness without the sharp peaks and crashes associated with isolated caffeine.
For private-label gummy brands, Guarana offers a clean-label positioning as a plant-based energy source. Its low cost tier and good gummy applicability make it an accessible active for brands targeting natural energy, mental focus, and pre-workout positioning. Because Guarana is a botanical on the EFSA on-hold list, brands must rely on co-formulated nutrients such as Vitamin B6, B12, or Magnesium to carry authorised energy-yielding metabolism claims on pack.
Origin and history
Guarana has been used for centuries by indigenous Amazonian tribes, particularly the Sateré-Maué people of Brazil, who prepared a paste from the seeds for its stimulating and medicinal properties. The plant was introduced to European markets in the 19th century and became popular in Brazil as a soft drink ingredient, where it remains a national staple.
Today, Guarana is cultivated primarily in Brazil, with smaller production in Venezuela and Colombia. The seeds are harvested, dried, and processed into either a fine powder or a standardised extract. Industrial production focuses on standardising caffeine content to ensure batch-to-batch consistency, typically ranging from 10% to 22% caffeine by weight.
Scientific overview
The primary active compound in Guarana is caffeine, known in this context as guaranine. Unlike synthetic caffeine, Guarana contains a complex matrix of other xanthines (theobromine, theophylline) and tannins that modulate its absorption and metabolism, resulting in a more gradual release of caffeine into the bloodstream. This sustained-release profile is the key differentiator from isolated caffeine sources.
Bioavailability of Guarana's caffeine is comparable to synthetic caffeine, but the presence of tannins may slow gastric emptying and prolong the absorption phase. Standardised extracts provide predictable caffeine content, while whole seed powder offers the full phytochemical profile but with less precise dosing. For gummy manufacturing, standardised extracts are preferred for consistent potency and reduced bitterness.
Manufacturing watchpoints include the bitter astringent taste, which requires robust flavour masking with sweet profiles such as berry, tropical fruit, or citrus. Guarana is heat-stable and soluble in gummy matrices, making it straightforward to incorporate. Cost-per-mg is low, particularly when compared to synthetic caffeine alternatives, though standardised extracts command a slight premium over raw powder.
Why brands use Guarana
Guarana occupies a strong position in the natural energy segment, appealing to consumers seeking plant-based alternatives to synthetic caffeine. It is commonly positioned alongside L-Theanine for smooth focus, Ginseng for adaptogenic energy, or CoQ10 for mitochondrial support. The sustained-release profile is a key selling point for brands targeting sustained mental alertness without jitters.
From a formulation and manufacturing perspective, Guarana is one of the most straightforward botanicals to work with in gummies. It is heat-stable, soluble, and compatible with standard gummy processing temperatures. The primary challenge is taste — the bitter astringency requires careful flavour engineering, typically with high-intensity sweeteners and fruit flavours. DAT's formulation team can recommend masking strategies per project.
For pack copy, brands should position Guarana around natural energy and mental alertness without making specific health claims. Because Guarana has no authorised claims under EU Regulation 432/2012, any health-related wording must be carried by co-formulated nutrients such as Vitamin B6 (contributes to normal energy-yielding metabolism) or Magnesium (contributes to normal functioning of the nervous system). DAT reviews claim strategy per project to ensure compliance with EU and UK regulations.
Formats this ingredient is reviewed for
DAT Supply covers gummy, capsule, softgel, tablet, powder, oral strip, liquid drop, shot, jelly and pet formats. The list below reflects every format this ingredient is reviewed for — chips link through to the manufacturing hub for each format. Final compatibility, dose and matrix are confirmed per project.
Formulation notes
Verified formulation reference across the formats this ingredient is reviewed for — the Supported formats section lists every product format this active is approved for, and the per-format Considerations section below covers matrix-specific guidance. Final formulation, dose and on-pack copy are confirmed per project.
- Gummy fit
- Good
- Heat stable
- Yes
- Soluble in matrix
- Yes
- Cost tier
- Low
Forms available
- dry extract (standardised to 10-22% caffeine)
- seed powder
Dosage reference
Brand positioning range typically 75-400 mg per serving. No EU NRV established for Guarana as a botanical. DAT confirms dosing per project based on target market and claim strategy.
Taste & sensory
Bitter astringent. Needs masking with sweet flavours such as berry, tropical fruit, or citrus.
Manufacturing notes
Gummy-optimised dosing and format considerations. Standardised extracts provide consistent caffeine content. Powder forms may require higher inclusion rates for efficacy.
Per-format formulation notes
Safe-baseline considerations for each format this ingredient is reviewed for. Final formulation, dose and on-pack copy are confirmed per project.
Gummies
- Taste masking and aroma load against the cooked-base flavour — confirmed per project.
- Heat exposure during cooking; coated or encapsulated forms may be required — confirmed per project.
- Matrix choice (pectin vs gelatin) and its effect on ingredient stability — confirmed per project.
- Per-gummy dose and serving count needed to hit the label claim — confirmed per project.
Sachets
- Powder flow and dose accuracy at single-serve sachet weights — confirmed per project.
- Barrier requirements (oxygen, moisture) for the active — confirmed per project.
- Reconstitution behaviour when the sachet is dosed into water — confirmed per project.
EU-authorised health claims
EU-authorised wording for this ingredient is reviewed per project against Reg. 1924/2006 and the authorised list under Reg. 432/2012. No final claim wording is implied by this page.
Authorised at ≥15% NRV per daily serving. Claim wording must appear verbatim on consumer packaging. DAT reviews final pack copy per project against EU 1924/2006 and the authorised list under EU 432/2012.
Guarana is a botanical ingredient on the EFSA on-hold list for health claims. No authorised claims exist under Reg. 432/2012. Brands should position around natural energy and mental alertness without making specific health claims. Caffeine content must be declared per EU FIC Regulation 1169/2011. DAT reviews claim strategy per project.
Studies & evidence
External peer-reviewed sources and regulatory opinions. Citations only — DAT does not endorse the publishers.
EFSA Panel on Dietetic Products, Nutrition and Allergies·EFSA Journal·2015
Haskell CF, Kennedy DO, Wesnes KA, Scholey AB·Journal of Psychopharmacology·2007
Kennedy DO, Haskell CF, Wesnes KA, Scholey AB·Nutritional Neuroscience·2004
Schimpl FC, da Silva JF, Gonçalves JF, Mazzafera P·Journal of Ethnopharmacology·2013
European Parliament and Council·Official Journal of the European Union·2011
Product concepts featuring Guarana
Private-label product concepts where Guarana appears in the formula. Each opens to a product brief and quote route.
Caffeine Focus Gummies
Caffeine Focus Gummies is a white-label pectin-gummy supplement concept for brands building a energy & focus range. Final positioning, claims and documentation are reviewed per project and target market.
Energy & Focus Guaraná Sachets
Energy & Focus Guaraná Sachets is a white-label sachet-based supplement concept for brands building a energy & focus range. Final positioning, claims and documentation are reviewed per project and target market.
Energy & Focus Nootropic Premium Sachets
Energy & Focus Nootropic Premium Sachets is a white-label sachet-based supplement concept for brands building a energy & focus range. Final positioning, claims and documentation are reviewed per project and target market.
Male Energy Gummies
Male Energy Gummies is a white-label pectin-gummy supplement concept for brands building a men's health range. Final positioning, claims and documentation are reviewed per project and target market.
Synergies & conflicts
Pairs well with
Pairs with L-Theanine (smooth energy), Ginseng (adaptogenic energy), CoQ10 (mitochondrial support).
Care when combining with
Caffeine side effects possible. Sustained release is advantage — less jittery than isolated caffeine.
Similar ingredients
Ingredients that frequently sit alongside this one in private-label supplement briefs.

Aloe Vera
Aloe Vera (Aloe barbadensis) is a succulent plant whose inner gel is used in food supplements for its hydrating and soothing properties. As a botanical on the EU on-hold list, it carries no authorised health claims under Reg. 432/2012. Brands typically position it around general wellness, digestive comfort, and skin hydration, often co-formulated with Vitamin C or probiotics for claim support.

Artichoke
Artichoke (Cynara scolymus) is a botanical ingredient used in dietary supplements for its traditional association with digestive and liver function. It is one of the most familiar and commercially understood botanical actives across EU and US markets. As a botanical on the EU on-hold list, no authorised health claims are currently permitted under Reg. 432/2012.

Arugula Extract
Arugula extract is a botanical ingredient derived from Eruca sativa leaves, used in gummy and sachet formats for green superfood and daily wellness positioning. It is a botanical on the EFSA on-hold list with no authorised health claims under Reg. (EU) 432/2012. Any claim coverage must come from co-formulated nutrients.

Ashwagandha
Ashwagandha (Withania somnifera) is a traditional Ayurvedic root used historically for stress, vitality, and sleep. In gummy formats it is most commonly positioned within stress-and-calm or sleep stacks. Ashwagandha sits on the EFSA "on-hold" list of botanical claims, with no authorised EU health claims of its own; substantiated claim wording in Ashwagandha gummies typically derives from co- formulated nutrients such as Magnesium and Vitamin B6.

Bacopa Extract
Bacopa Extract (Bacopa monnieri) is a botanical ingredient traditionally used in Ayurvedic wellness systems. In private-label gummy manufacturing, it is positioned for cognitive support, memory, and stress resilience. Bacopa has no EFSA-authorised health claims under Reg. 432/2012; claim coverage for cognitive function relies on co-formulated nutrients such as Vitamin B6, B12, or Iron.

Bamboo Extract
Bamboo extract is a plant-derived ingredient standardised for silica content, sourced from Bambusa vulgaris. It is used in gummy and sachet formulations as a natural source of silicon, a mineral involved in connective tissue structure. Under EU Regulation 432/2012, bamboo extract carries no authorised health claims; brands typically co-formulate with Biotin, Zinc, or Vitamin C for hair, skin, and nails positioning.
Adjacent reading
Pairings, resource guides and blog notes most often associated with Guarana on DAT Supply briefs.
Develop a formula featuring Guarana
A ready white-label formula exists — open a product brief, or talk to our team to align the launch plan.